(Planet Comics 004, 1940)
Flint Baker and co are making their return trip from Mars and due to an unscheduled diversion to Pluto in Planet Comics 003 they end up passing Jupiter on the way, at which point they are forced to make landfall to avoid an attack by outer space organisms referred to as "stratosphere serpents" despite being more like starfish crossed with octopuses. While there, Flint and gal pal Mimi Wilson do a bit of exploring and discover the city of Zu, inhabited by a wretched mass of oppressed Jovians and ruled over by the Great Intelligence.
The Great Intelligence is... probably a rogue AI of some description? It watches over the city via the Great Eye, listens with the Great Ear and issues orders with the Great Mouth. It also has flamethrowing capacity. (the reason I hesitate to conclusively say that the Intelligence is a machine is what the Jovian says in the first panel to feature the Great Eye: "our master has lost all human identity." This could easily be interpreted as a bit of flowery language to describe the declining relationship between the city's inhabitants and the machines that run it, but how weird and cool would it be if the whole operation was wired into some wizened cyborg in the middle of everything? And as the comic does not bother to resolve the question it could be either, though given the roasting of that poor old man we can at least confirm a distinct lack of humanity)
Baker manages to fry the Great Eye with his ray gun, upon which we meet the final piece of the city gestalt: its Will, embodied as a bunch of beefy cyborgs.
For fomenting discord in Zu, Flint and Mimi are sentenced to death via being ground up and fed to the Great Mouth (and this unusually grotesque method of execution did contribute to my theories about the Intelligence having an at least partially organic makeup, thanks for noticing)! Lucky for them, then, that Mimi stumbles upon the Will's one weakness: a thin exposed wire at the back of their necks. They escape their fate in the grinder, destroy the Great Ear and Great Mouth, and evacuate the surviving citizens of Zu back to Earth with them.
But what of the Great Intelligence itself? Certainly all of its external organs are gone, but the mind itself... who knows?